现任温州医学院病理生理学教研室主任，兼任世界华人医学联合会副理事长、中华临床医学会常务理事、中华名医协会理事、浙江省温州市生理科学会常务理事、中华医学实践杂志常务编委、中华实用医学杂志编委、中华中西医杂志编委、中华全科医学杂志编委、中国临床康复杂志编委、中国中医药学刊特邀编委等职业。

张铁华，男，1970年10月出生，工学博士，吉林大学食品科学与工程学院院长，教授，博士生导师。先后主持和承担国家、吉林省科技厅等各类课题20多项。发表论文60余篇，其中SCI\EI收录30多篇，获得国家发明专利12项，获奖6项，参与编写高校教材等10余部。 研究方向 （1）活性蛋白、功能肽的分离制备及活性研究；（2）功能性乳制品研究与开发；（3）食品生物技术。  社会兼职 吉林省饮食文化研究会副会长 吉林省食品学会常务理事 吉林省农特产品加工协会常务理事 中国畜产品加工研究会乳品加工专业委员会委员 中国研究型医院学会空间微生物学与感染专业委员会委员 《食品研究与开发》、《食品工业科技》编委 学术论文 编辑 (1)Jie Zhang, Tiezhu Li, Tuoyi Wang, Cuiping Yuan, Shuning Zhong, Tianzhu Guan, Zhuolin Li, Yongzhi Wang, Hansong Yu, Quan Luo, Yongjun Wang*,Tiehua Zhang*.Estrogenicity of halogenated bisphenol A: in vitro and in silico investigations. Archives of Toxicology, 2018, 92(3): 1215-1223.(1区IF=5.901) (2)Chunyan Sun, Ruifang Su, Jiaxin Bie, Hongjing Sun, Shangna Qiao, Xinyue Ma, Rui Sun,Tiehua Zhang*. Label-free fluorescent sensor based on aptamer and thiazole orange for the detection of tetracycline. Dyes and Pigments, 2018, 149: 867–875.(1区IF=3.473) (3)Haiqing Ye, Qian Li, Zhengzhe Zhang, Maocheng Sun, Changhui Zhao,Tiehua Zhang*. Effect of a novel potential probioticLactobacillus paracaseiJlus66 isolated from fermented milk on nonalcoholic fatty liver in rats. Food & Function, 2017, 8(12): 4539-4546.(1区IF=3.247) (4)Jie Zhang, Tiezhu Li, Tuoyi Wang, Tianzhu Guan, Hansong Yu, Zhuolin Li, Yongzhi Wang, Yongjun Wang*,Tiehua Zhang*. Binding interactions of halogenated bisphenol A with mouse PPARα: in vitro investigation and molecular dynamics simulation. Toxicology Letters, 2018, 283: 32-38.(2区IF=3.858)(5)Tianzhu Guan, Yonghai Sun, Hansong Yu, Tiezhu Li, Jie Zhang*,Tiehua Zhang*.A fluorescence polarization assay for bisphenol analogues in soybean oil using glucocorticoid receptor. European Journal of Lipid Science and Technology, 2017, 119(9): 1700042.(3区IF=2.145) (6)Diru Liu,Tiehua Zhang*, Nan Jiang, Chunyu Xi, Chunyan Sun, Jian Zheng, Mingruo Guo. Effects of encapsulated fish oil by polymerized whey protein on the textural and sensory characteristics of low-fat yogurt. Polish Journal of Food and Nutrition Sciences, 2016, 66(3): 189-198.(4区IF=1.276) (7)Tiehua Zhang, James McCarthy, Guorong Wang, Yanyan Liu, Mingruo Guo*. Physiochemical properties, microstructure, and probiotic survivability of nonfat goats' milk yogurt using heat-treated whey protein concentrate as fat replacer. Journal of Food Science, 2015, 80(4): M788-M794.(3区IF=1.815) (8)Tiehua Zhang, Shaojun Wang, Jian Zheng, Feng Gao, Sarfraz Ahmad, Mingruo Guo*. Microencapsulation ofLactobacillus acidophilus(La-5), its evaluation and application in the yoghurt. Pakistan Journal of Agricultural Sciences, 2016, 53(4): 933-939.(3区IF=0.609) (9)Jie Zhang,Tiehua Zhang, Tianzhu Guan, Ping Ruan, Dayong Ren, Weichang Dai, Hansong Yu*, Tiezhu Li*.Spectroscopic and molecular modeling approaches to investigate the interaction of bisphenol A, bisphenol F and their diglycidyl ethers with PPARα. Chemosphere, 2017, 180: 253-258.(2区IF=4.208) (10)Jie Zhang,Tiehua Zhang, Tianzhu Guan, Hansong Yu*, Tiezhu Li*. In vitro and in silico assessment of the structure-dependent binding of bisphenol analogues to glucocorticoid receptor. Analytical and Bioanalytical Chemistry, 2017, 409(8): 2239-2246.(2区IF=3.431) (11)Suxia Shen,Tiehua Zhang, Yuan Yuan, Songyi Lin, Jingyue Xu, Haiqing Ye*.Effects of cinnamaldehyde onEscherichia coliandStaphylococcus aureusmembrane. Food Control, 2015, 47: 196-202.(2区IF=3.496) (12)Jie Zhang, Tiezhu Li,Tiehua Zhang, Peiyu Xue, Tianzhu Guan, Yuan Yuan, Hansong Yu*. Receptor-based fluorescence polarization assay to detect phthalate esters in Chinese spirits. Food Analytical Methods, 2017, 10(5): 1293-1300.(2区IF=2.038) (13)Tianzhu Guan, Yonghai Sun,Tiehua Zhang, Tiezhu Li, Zhuolin Li, Yue Zhang, Jie Zhang*, Yongjun Wang*.Simultaneous determination of bisphenol A and its halogenated analogues in soil by fluorescence polarization assay. Journal of Soils and Sediments, 2018, 18(3): 845-851.(3区IF=2.522) (14)Songyi Lin, Rong Liang,Tiehua Zhang, Yuan Yuan, Suxia Shen, Haiqing Ye*. Microarray analysis of the transcriptome of theEscherichia coli(E. coli) regulated by cinnamaldehyde (CMA). Food and Agricultural Immunology, 2017, 28(3): 500-515.(3区IF=1.392) (15)Yujun Jiang, Zhe Zheng,Tiehua Zhang, Gregory Hendricks, Mingruo Guo*. Microencapsulation ofLactobacillus acidophilusNCFM using polymerized whey proteins as wall material. International Journal of Food Sciences and Nutrition, 2016, 67(6): 670-677.(4区IF=1.444) (16)Tianzhu Guan, Tiezhu Li,Tiehua Zhang, Zhuolin Li, Yongzhi Wang, Hansong Yu, Ping Ruan, Jie Zhang*, Yongjun Wang*. Fluorescence polarization assay for the simultaneous determination of bisphenol A, bisphenol F and their diglycidyl ethers in canned tuna. International Journal of Food Properties, 2017, 20(S2): 1920-1929.(4区IF=1.427) (17)Cuina Wang, Feng Gao,Tiehua Zhang, Yulong Wang, Mingruo Guo*. Physiochemical, textural, sensory properties and probiotic survivability of Chinese Laosuan Nai (protein-fortified set yoghurt) using polymerised whey protein as a co-thickening agent. International journal of dairy technology, 2015, 68(2): 261-269.(4区IF=0.813) (18)Mu Wang, Feng Gao, Huajie Zheng,Tiehua Zhang, Mingruo Guo*. Microencapsulation of ginsenosides using polymerised whey protein (PWP) as wall material and its application in probiotic fermented milk. International Journal of Food Science & Technology, 2017, 52(4):1009-1017.(3区IF=1.640) (19)Zhang Tie-hua,Zhang Xin-yu,Tian Mu,Zhong Shu-ning,Du Zhi-yang.Optimization of Mixed Fermentation Conditions by Mixed Culture of Kefir and Bacillus. Applied Mechanics and Materials (EI). 2014，18:303-310. (20)张铁华，李玺，叶海青，车宇飞，田路，于亚莉*.发酵林蛙油饮品的研制及工艺优化.吉林大学学报(工学版，EI收录) 2013，3(6):1719-1724. (21)张铁华，姜楠，张兴，王君宝，马琳，宋开永，刘迪茹，郭明若*.聚合乳清蛋白包埋油脂功能特性的研究.食品科学技术学报2013，(2) : 21-25. (22)关丰睿，孙春燕，车宇飞，叶海清，李玺，王少君，张铁华*.凝固型林蛙油营养酸奶的配方优化及贮藏稳定性研究.食品工业科技2014，5(02)179-182. (23)梁海艳，张铁华*，郑健，郭明若，王少君，刘迪茹，陈璐，田路，王翠娜.人参多糖对乳酸菌发酵及酸奶质构特性的影响.中国乳品工业2013，1(1)21-24. (24)孙春燕，张民伟，李宏坤，李岩松，平红，郭佳佳，张铁华*.金纳米粒子比色探针检测牛奶及鸡蛋中的三聚氰胺.分析化学(SCI收录) 2012，0(3): 323-327. (25)Hou, Pingping; Wang, Gang; Li, Dongxue; Zhang, Ting; Li, Xudong; Zhou, Xinhui ;Zhang, Tiehua*.THE STABILITY OF GINSENG WHEY PROTEIN POLYPEPTIDE BEVERAGE,PROCEEDINGS OF THE 2016 INTERNATIONAL CONFERENCE ON BIOTECHNOLOGY & MEDICAL SCIENCE,2017: 98-103 (26)Hou, Pingping; Wang, Gang; Zhou, Xinhui; Zhang, Ting; Li, Dongxue; Li, Xudong;Zhang, Tiehua*.THE FORMULA AND TECHNOLOGY OPTIMIZATION OF GINSENG WHEY PROTEIN POLYPEPTIDE BEVERAGE,PROCEEDINGS OF THE 2016 INTERNATIONAL CONFERENCE ON BIOTECHNOLOGY & MEDICAL SCIENCE,2017: 579-584 (27)张铁华,姜楠,刘迪茹,郝锦峰,毛春玲,郭明若.乳清蛋白基质脂肪替代物的制备及其在低脂液态奶中的应用，吉林大学学报(工学版)，2015,45(3):1024-1028.(EI收录) (28)Tiehua Zhang, Yufei Che, Haiyang Yan, Lu Tian, Haiqing Ye*,Xi Li, Zhuojun Jiang and Xinyu Zhang .The effect of oviductus rana hydrolysate on the immunity function of low-immunity mice.Advanced Materials Research Vols. 781-784 (2013):1248-1254.（EI收录） (29)Tiehua Zhang, Zhuodan Zhang, Haiyang Yan, Da Li, Zhennai Yang, Mingruo Guo. Effects of Stabilizers and exopolysaccharides on physiochemical properties of fermented skim milk by Streptococcus thermophilus ST1. African Journal of Biotechnology,2012,11(22): 6123-6130. (SCI收录，IF 0.632) (30)Hong Ping,Minwei Zhang,Hongkun Li,Shugui Li,Quansi Chen,Chunyan Sun,Tiehua Zhang*.Visual detection of melamine in raw milk by label-free silver nanoparticles,Food Control, 2012, 23(1): 191-197.(ESI高引用论文，IF2.812) (31)Hong Zhuang,Tiehua Zhang,Jingbo Liu,Yuan Yuan. Detection of acrylamide content in traditional Chinese food by high-performance liquid chromatography tandem mass spectrometry method, CYTA-JOURNAL OF FOOD,2012,10(1)36-41.(SCI收录，IF0.5) (32)Tiehua Zhang, Chunhong Zhang,Shengyu Li, Yanchun Yang, Zhennai Yang.Growth and exopolysaccharide production by Streptococcus thermophilus ST1 in skim milk. Brazilian Journal of Microbiology. 2011,42(4):1470-1478. (SCI收录，IF 0.632) (33)Zhang Tie-hua, Zheng Jian,Zhang Zhuo-dan,Luo Xiang-dan,Liang Hai-yan,Ye Hai-qing,Liu Jing-bo.The purification technology and antimicrobial activity analysis of antimicrobial peptide from Ovotransferrin，Chemical Research in Chinese Universities, 2011，27(3):361-365.（SCI收录，IF 0.556） (34)Cuina Wang,Tiehua Zhang (并列第一作者), Jun Liu, Shuang Lu, Cheng Zhang, Erlei Wang, Zuozhao Wang, Yan Zhang, Jingbo Liu.Subchronic toxicity study of corn silk with rats,Journal of Ethnopharmacology, 2011,137(1):36- 43.(SCI收录，IF 2.322) (35)Feng Gao, Haiqing Ye, Yali Yu,Tiehua Zhang, Xuming Deng.Lack of toxicological effect through mutagenicity test of polyphenol extracts from peanut shells, Food Chemistry, 2011,129:920–924.(SCI收录，IF4.052) (36)张铁华,王少君,刘迪茹,肇萍,于亚莉.脉冲电场提取“西藏灵菇”胞外多糖条件优化，吉林大学学报（工学版），2011,41(3):882-886.(EI收录) (37)罗翔丹,姚刚,张铁华*. 3种真菌多糖对嗜酸乳杆菌发酵特性的影响,吉林大学学报(医学版). 2011, 37(6): 1047-1050. (38)郑健,张铁华*,张春红,张卓丹,陈玉江.卵转铁蛋白制备抗菌活性肽的研究,中国兽医学报,2010,30(10):1358-1362 (39)Yuan Yuan, Hong Zhuang,Tiehua Zhang*, Jingbo Liu.Patulin content in apple products marketed in Northeast China，Food Control, 2010,21(11):1488-1491.（SCI收录，IF2.812） (40)殷涌光,张铁华,刘静波,庄红,闫海洋,陈玉江,张婷.高压脉冲电场（PEF）对溶菌酶抑菌活性的影响，吉林大学学报（工学版），2008,38(6):1485-1488. (EI收录) 

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